The Madness of Dr. Tube (1915)

A wacky scientist develops a powder that he believes will have the effect of distorting reality for those who take it. To test its effect, he tries it out on his boy assistant, his pets, his nieces, and their beaus. But, chaos ensues as his nieces don't find their appearances as funny as the rest, so Doctor Tube tries to find a way to make things right.